Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HMGCR | P04035 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228436 | 0.91 | CYP3A4 (0.47) | CYP3A4L3MBTL1HMGCRGAAKMT2A | |
| SCHEMBL27536442 | 0.85 | CYP3A4 (0.56) | CYP3A4L3MBTL1HMGCRGAAKMT2A | |
| SCHEMBL11526769 | 0.83 | CYP3A4 (0.42) | CYP3A4L3MBTL1HMGCRGAAKMT2A | |
| SCHEMBL28305121 | 0.81 | CYP3A4 (0.54) | CYP3A4L3MBTL1HMGCRGAANR1I2 | |
| SCHEMBL914599 | 0.81 | HMGCR (0.50) | CYP3A4L3MBTL1HMGCRGAAKMT2A | |
| SCHEMBL10984731 | 0.80 | HMGCR (0.49) | CYP3A4HMGCRGAAKMT2AMEN1 | |
| SCHEMBL10989164 | 0.79 | HMGCR (0.51) | CYP3A4HMGCRGAAKMT2AMEN1 | |
| SCHEMBL11154052 | 0.79 | HMGCR (0.48) | CYP3A4HMGCRGAAKMT2AMEN1 | |
| SCHEMBL2679600 | 0.79 | CYP3A4 (0.40) | CYP3A4L3MBTL1HMGCRGAAKMT2A | |
| SCHEMBL21814199 | 0.79 | HMGCR (0.48) | CYP3A4HMGCRGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510633-A1 | Lubricating oil composition and use thereof | JAPAN SUN OIL COMPANY, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |