Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HMGCR | P04035 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659019 | 0.83 | CYP3A4 (0.47) | CYP3A4L3MBTL1HMGCRLMNATSHR | |
| SCHEMBL11529863 | 0.81 | LMNA (0.38) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11528379 | 0.81 | LMNA (0.38) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11526814 | 0.81 | LMNA (0.38) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11527969 | 0.81 | LMNA (0.38) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11803366 | 0.80 | HMGCR (0.46) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11478273 | 0.78 | CYP3A4 (0.50) | CYP3A4L3MBTL1LMNATSHRHTR1A | |
| SCHEMBL6228436 | 0.77 | CYP3A4 (0.47) | CYP3A4L3MBTL1HMGCRLMNATSHR | |
| SCHEMBL11527505 | 0.76 | LMNA (0.34) | CYP3A4HMGCRLMNATSHRHTR1A | |
| SCHEMBL11533049 | 0.75 | CYP2C19 (0.44) | CYP3A4HMGCRLMNATSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161473-A | 2,4,6-Trialkyl-3-hydroxyphenylalkane phosphonate and phosphinate stabilizers | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-3962376-A | STABILIZERS, OXIDATION RESISTANCE, HEAT RESISTANCE, RADIATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
| US-3951912-A | Hydroxybenzylphosphonate antioxidants | AMERICAN CYANAMID COMPANY (US) | 1976-04-20 | — | — | US | disclosed |