Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659299 | 1.00 | NR1I2 (0.49) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15920930 | 1.00 | NR1I2 (0.49) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL18831801 | 1.00 | NR1I2 (0.49) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL29020295 | 0.98 | NR1I2 (0.50) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15434618 | 0.94 | NR1I2 (0.54) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14115082 | 0.94 | NR1I2 (0.54) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL28133680 | 0.87 | S1PR1 (0.52) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL10182480 | 0.87 | FKBP1A (0.51) | NR1I2LTA4HCYP3A4CYP2D6KCNH2 | |
| SCHEMBL9649182 | 0.87 | FKBP1A (0.51) | NR1I2LTA4HCYP3A4CYP2D6KCNH2 | |
| SCHEMBL18482504 | 0.87 | FKBP1A (0.51) | NR1I2LTA4HCYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309624-B1 | COMPOSITION FOR ENHANCING PERCUTANEOUS ADMINISTRATION OF MEDICINE | NITTO DENKO CORPORATION (JP) | 1992-03-11 | — | — | EP | disclosed |
| EP-0309624-A1 | Composition for enhancing percutaneous administration of medicine | NITTO DENKO CORPORATION (JP) | 1989-04-05 | — | — | EP | disclosed |