Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658295 | 0.89 | P2RX7 (0.47) | CREBBPBRD4CYP2C19MAPK1P2RX7 | |
| Water SCHEMBL9660273 | 0.88 | MAPK1 (0.57) | CREBBPBRD4CYP2C19MAPK1EP300 | |
| Water SCHEMBL9658350 | 0.88 | P2RX7 (0.53) | CREBBPBRD4CYP2C19MAPK1EP300 | |
| Water SCHEMBL9658363 | 0.86 | CREBBP (0.47) | CREBBPBRD4MAPK1EP300P2RX7 | |
| Water SCHEMBL9660071 | 0.79 | HTR2A (0.47) | CREBBPBRD4MAPK1EP300KCNK3 | |
| SCHEMBL9658344 | 0.78 | HTR2A (0.53) | CREBBPBRD4MAPK1P2RX7KCNK3 | |
| Hydrochloric Acid SCHEMBL9658199 | 0.76 | MAPK1 (0.57) | CREBBPBRD4MAPK1EP300P2RX7 | |
| Water SCHEMBL9660093 | 0.74 | BRD4 (0.46) | CREBBPBRD4MAPK1KCNK3BAZ2B | |
| SCHEMBL183240 | 0.73 | HTR2A (0.57) | CREBBPBRD4MAPK1KCNK3BAZ2B | |
| SCHEMBL10817743 | 0.72 | MAPK1 (0.80) | CREBBPBRD4MAPK1EP300BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137890-A | Gastrointestinal disorders, antiulcer agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |