Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.48 |
| ▸ | ADH1A | P07327 | 2/20 | 0.48 |
| ▸ | ADH4 | P08319 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388595 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL270646 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL11337999 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL303029 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9661097 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9661652 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9660996 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL302861 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL59943 | 0.98 | ADH1C (0.45) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL10934343 | 0.93 | ADH1C (0.47) | ADH1CADH1AADH4DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517262-A1 | Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-09 | — | — | EP | disclosed |