Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573926 | 0.93 | ADRB2 (0.63) | MEN1KMT2AADRB2KDM4EGAA | |
| SCHEMBL6623043 | 0.93 | ADRB2 (0.63) | MEN1KMT2AADRB2KDM4EGAA | |
| SCHEMBL15994144 | 0.93 | ADRB2 (0.63) | MEN1KMT2AADRB2KDM4EGAA | |
| SCHEMBL2297575 | 0.93 | MEN1 (0.60) | NPC1ALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL2296960 | 0.93 | MEN1 (0.60) | NPC1ALDH1A1MEN1KMT2AADRB2 | |
| Hydrochloric Acid SCHEMBL19571212 | 0.92 | ADRB2 (0.61) | MEN1KMT2AADRB2KDM4EGAA | |
| Hydrochloric Acid SCHEMBL1405434 | 0.92 | ADRB2 (0.61) | MEN1KMT2AADRB2KDM4EGAA | |
| Sulfuric Acid SCHEMBL28838446 | 0.88 | ADRB2 (0.57) | MEN1KMT2AADRB2KDM4ECA12 | |
| Sulfuric Acid SCHEMBL28838447 | 0.88 | ADRB2 (0.57) | MEN1KMT2AADRB2KDM4ECA12 | |
| SCHEMBL16796557 | 0.85 | NPC1 (0.60) | NPC1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307121-B1 | SULPHONAMIDE ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1992-03-18 | — | — | EP | disclosed |
| EP-0307121-A1 | Sulphonamide antiarrhythmic agents | Pfizer Limited (GB) | 1989-03-15 | — | — | EP | disclosed |