Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.54 |
| ▸ | PGC | P20142 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658139 | 0.93 | REN (0.55) | RENPGC | |
| SCHEMBL9659392 | 0.91 | REN (0.53) | RENPGCKDM4E | |
| SCHEMBL9659594 | 0.89 | REN (0.54) | REN | |
| SCHEMBL9437961 | 0.89 | REN (0.64) | REN | |
| SCHEMBL9438012 | 0.89 | REN (0.58) | RENPGC | |
| SCHEMBL7376775 | 0.89 | REN (0.53) | RENPGC | |
| SCHEMBL9438106 | 0.88 | REN (0.57) | RENPGC | |
| SCHEMBL9438137 | 0.88 | REN (0.58) | RENPGC | |
| SCHEMBL9659590 | 0.88 | REN (0.56) | REN | |
| SCHEMBL9658127 | 0.88 | REN (0.52) | RENPGCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490259-A2 | Aminoacid and peptid derivatives with renin inhibiting properties | MERCK PATENT GmbH (DE) | 1992-06-17 | — | — | EP | disclosed |