Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659616 | 0.93 | REN (0.52) | REN | |
| SCHEMBL9659621 | 0.92 | REN (0.59) | REN | |
| SCHEMBL9660051 | 0.91 | REN (0.55) | REN | |
| SCHEMBL9660746 | 0.89 | REN (0.64) | REN | |
| SCHEMBL9676740 | 0.89 | REN (0.64) | REN | |
| SCHEMBL9660753 | 0.87 | REN (0.54) | REN | |
| SCHEMBL9674770 | 0.87 | REN (0.63) | REN | |
| SCHEMBL9658151 | 0.86 | REN (0.59) | REN | |
| SCHEMBL9658144 | 0.86 | REN (0.59) | REN | |
| SCHEMBL9270343 | 0.86 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490259-A2 | Aminoacid and peptid derivatives with renin inhibiting properties | MERCK PATENT GmbH (DE) | 1992-06-17 | — | — | EP | disclosed |