Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL9660778 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRD1 | |
| SCHEMBL971917 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL4283706 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL12026599 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL1477254 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL971919 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL29744950 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8784745 | 0.96 | OPRM1 (0.57) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11461369 | 0.84 | OPRM1 (0.46) | OPRM1OPRK1OPRD1 | |
| SCHEMBL5137090 | 0.84 | OPRM1 (0.46) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506468-A1 | N-substituted 4-phenyl-piperidine opioid-antagonists | ELI LILLY AND COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |