Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662441 | 0.95 | CA12 (0.54) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9662376 | 0.92 | CA2 (0.56) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9661612 | 0.87 | CA2 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9661527 | 0.86 | POLB (0.44) | CA2CA1CA9CA12CA7 | |
| SCHEMBL4899940 | 0.85 | POLB (0.57) | CA2POLBMAPTGAA | |
| SCHEMBL29599655 | 0.85 | POLB (0.57) | CA2POLBMAPTGAA | |
| SCHEMBL7179931 | 0.83 | CA12 (0.56) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9661565 | 0.82 | POLB (0.52) | CA2CA1POLBALDH1A1LMNA | |
| SCHEMBL931816 | 0.81 | CA12 (0.72) | CA2CA1CA9CA12CA7 | |
| SCHEMBL6900466 | 0.81 | CA12 (0.72) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |