SCHEMBL9660880

SCHEMBL9660880

COc1ccc(S(=O)(=O)c2ccc(OC(C)=O)c(C)c2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.57
TSHR P16473 4/20 0.54
POLB P06746 2/20 0.54
MAPK1 P28482 2/20 0.54
LMNA P02545 2/20 0.51
PKM P14618 2/20 0.49
MAPT P10636 1/20 0.49
GAA P10253 2/20 0.47
ALDH3A1 P30838 1/20 0.47
USP2 O75604 1/20 0.47
NPC1 O15118 1/20 0.46
NAMPT P43490 1/20 0.46
JUN P05412 1/20 0.46
NFKB1 P19838 1/20 0.46
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071602 0.87 TSHR (0.70) KMT2ATSHRPOLBMAPK1LMNA
SCHEMBL18052473 0.84 TSHR (0.73) KMT2ATSHRPOLBMAPK1LMNA
SCHEMBL9914234 0.82 TSHR (0.63) KMT2ATSHRPOLBMAPK1LMNA
SCHEMBL9661628 0.81 KMT2A (0.51) KMT2ATSHRPOLBLMNAPKM
SCHEMBL9661752 0.81 GAA (0.59) TSHRPOLBMAPK1LMNAPKM
SCHEMBL4348248 0.81 KMT2A (0.52) KMT2ATSHRPOLBLMNAPKM
SCHEMBL8490520 0.81 TSHR (0.58) KMT2ATSHRPOLBMAPK1LMNA
SCHEMBL9660843 0.80 KMT2A (0.56) KMT2ATSHRPOLBMAPK1LMNA
SCHEMBL10016827 0.80 CFD (0.54) KMT2ATSHRGAAJUNNFKB1
SCHEMBL12341779 0.80 TSHR (0.61) TSHRPOLBMAPK1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9864284-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-09 US disclosed
US-20160252829-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-09-01 US disclosed
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed
EP-0466096-A1 Derivatives of 4-hydroxyphenylsulfone JUJO PAPER CO., LTD. (JP) 1992-01-15 EP disclosed