Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662533 | 0.90 | ADRB2 (0.63) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL10661718 | 0.90 | ADRB2 (0.63) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL9664001 | 0.90 | ADRB2 (0.63) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL11138603 | 0.89 | ADRB2 (0.59) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL10658025 | 0.89 | ADRB2 (0.59) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL11174404 | 0.88 | ADRB2 (0.61) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL10659713 | 0.88 | ADRB2 (0.58) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL4384736 | 0.88 | ADRB2 (0.71) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL4384732 | 0.88 | ADRB2 (0.71) | ADRB2CASP3CASP6ADRB1ADRB3 | |
| SCHEMBL10661301 | 0.87 | ADRB2 (0.57) | ADRB2CASP3CASP6ADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244062-A2 | Use of aryl ethanol amine derivatives in the treatment of atherosclerosis | BEECHAM GROUP PLC (GB) | 1987-11-04 | — | — | EP | claimed |
| EP-0214221-A1 | ETHANOLAMINE DERIVATIVES FOR ADMINISTERING TO LIVESTOCK. | BEECHAM GROUP PLC (GB) | 1987-03-18 | — | — | EP | claimed |
| WO-1986005075-A1 | METHOD OF ADMINISTERING ETHANOLAMINE DERIVATIVES TO LIVESTOCK | BEECHAM GROUP P.L.C. (GB) | 1986-09-12 | — | — | WO | claimed |
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | claimed |
| US-5087626-A | METHOD FOR INCREASING THE WEIGHT GAIN AND IMPROVING THE FEED UTILIZATION EFFICIENCY OF LIVESTOCK | BEECHAM GROUP P.L.C (GB) | 1992-02-11 | — | — | US | disclosed |
| US-4880834-A | ANIMAL GROWTH REGULATORS | BEECHAM GROUP P.L.C. (GB) | 1989-11-14 | — | — | US | disclosed |
| US-4873240-A | Method for administering ethanolamine derivatives to livestock | BEECHAM GROUP P.L.C. (GB) | 1989-10-10 | — | — | US | disclosed |
| US-4753962-A | HYPOGLYCEMIC, ANTIOBESITY AGENT | BEECHAM GROUP P.L.C. (GB) | 1988-06-28 | — | — | US | disclosed |
| EP-0244062-A2 | Use of aryl ethanol amine derivatives in the treatment of atherosclerosis | BEECHAM GROUP PLC (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4654371-A | ANTI-OBESITY, HYPOGLYCEMIA AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-31 | — | — | US | disclosed |
| EP-0214221-A1 | ETHANOLAMINE DERIVATIVES FOR ADMINISTERING TO LIVESTOCK. | BEECHAM GROUP PLC (GB) | 1987-03-18 | — | — | EP | disclosed |
| WO-1986005075-A1 | METHOD OF ADMINISTERING ETHANOLAMINE DERIVATIVES TO LIVESTOCK | BEECHAM GROUP P.L.C. (GB) | 1986-09-12 | — | — | WO | disclosed |
| US-4478849-A | HYPERGLYCEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1984-10-23 | — | — | US | disclosed |
| EP-0006735-B1 | SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |