Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741408 | 0.88 | ADORA2A (0.41) | PNPHPRT1ADORA2AADORA2BADORA1 | |
| SCHEMBL9663817 | 0.86 | PNP (0.36) | PNPMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9740365 | 0.85 | PNP (0.36) | PNPHPRT1ADORA2AADORA2BADORA1 | |
| SCHEMBL9661238 | 0.80 | PNP (0.61) | PNPHPRT1ADORA2AADORA2BADORA1 | |
| SCHEMBL10737386 | 0.75 | PNP (0.70) | PNPHPRT1MEN1ALDH1A1LMNA | |
| SCHEMBL9742000 | 0.75 | PNP (0.34) | PNP | |
| SCHEMBL10743970 | 0.73 | PNP (0.37) | PNPMEN1ALDH1A1LMNACYP3A4 | |
| Ganciclovir SCHEMBL14491348 | 0.73 | BLM (0.60) | PNPHPRT1ADORA2AADORA1MEN1 | |
| SCHEMBL9740556 | 0.73 | PNP (0.34) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL11011339 | 0.68 | PNP (0.33) | PNPMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | claimed |
| US-4806642-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | claimed |
| EP-0145207-B1 | PURINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0145207-A1 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | claimed |
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0249249-B1 | GLYCEROL DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4921859-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4918219-A | Glycerine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4806642-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0145207-B1 | PURINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0249249-A2 | Glycerol derivatives | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0249247-A2 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0249248-A2 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0145207-A1 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |