Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405065 | 0.83 | SMN1; SMN2 (0.72) | RAB9ASMN1; SMN2NPC1GAALMNA | |
| SCHEMBL12139525 | 0.83 | SMN1; SMN2 (0.72) | RAB9ASMN1; SMN2NPC1GAALMNA | |
| Hydrochloric Acid SCHEMBL28953557 | 0.81 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1GAALMNA | |
| SCHEMBL12139494 | 0.77 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1GAALMNA | |
| SCHEMBL9662649 | 0.76 | PRMT5 (0.75) | GAALMNAHPGDNPSR1ALDH1A1 | |
| SCHEMBL17667029 | 0.75 | PARP1 (0.55) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL17667033 | 0.75 | PARP1 (0.55) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL17667030 | 0.73 | PARP1 (0.56) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL9663389 | 0.73 | PRMT5 (0.56) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL17667032 | 0.73 | PARP1 (0.56) | RAB9ANPC1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110808-A | Aldose reductase inhibitors; peripheral effects of diabetes and galactosemia | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1992-05-05 | — | — | US | claimed |