Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321090 | 1.00 | GCGR (0.40) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9320007 | 0.89 | GCGR (0.43) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9662660 | 0.88 | GCGR (0.39) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9319169 | 0.88 | GCGR (0.39) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9321315 | 0.86 | AR (0.43) | KDM4EALDH1A1TDP1L3MBTL1AR | |
| SCHEMBL9664046 | 0.86 | AR (0.43) | KDM4EALDH1A1TDP1L3MBTL1AR | |
| SCHEMBL9319453 | 0.84 | ALDH1A1 (0.36) | GCGRHMGCRKDM4EALDH1A1TDP1 | |
| SCHEMBL9318703 | 0.79 | GCGR (0.58) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9662639 | 0.79 | HMGCR (0.53) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL9662629 | 0.79 | HMGCR (0.53) | GCGRHMGCRESR1CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164506-A | Substituted 2-pyridones and pyrid-2-thiones compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |