Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777379 | 0.78 | SIGMAR1 (0.60) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL12846708 | 0.76 | CHRM2 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7290398 | 0.75 | SIGMAR1 (0.55) | SIGMAR1DRD2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL10566456 | 0.74 | SIGMAR1 (0.49) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL24994297 | 0.72 | CYP2D6 (0.55) | SIGMAR1CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL1042820 | 0.71 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL10567177 | 0.71 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL28978295 | 0.71 | MEN1 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL1223370 | 0.70 | SIGMAR1 (0.52) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL1344124 | 0.70 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157038-A | Antidepressants; tranquilizers; treatment of schizophrenia and epilepsy; antilepmic agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-10-20 | — | — | US | disclosed |