Asparagine

Asparagine

SCHEMBL9664240

CCCCCCCCCCCCCC(=O)NC(CC(N)=O)C(=O)O.NC(=O)CC(N)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 15/20 0.65
EPHX2 P34913 2/20 0.50
SLC6A5 Q9Y345 2/20 0.50
MEN1 O00255 1/20 0.47
FAAH O00519 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL9664230 1.00 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
Aspartic Acid SCHEMBL25230460 0.95 NOD1 (0.62) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL6536277 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL17204105 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL13279250 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL25175260 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL21724206 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL21724210 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL21724437 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH
SCHEMBL7702846 0.93 NOD1 (0.65) NOD1EPHX2SLC6A5MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473700-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1992-03-11 EP claimed
WO-1990014429-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1990-11-29 WO claimed