Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821080 | 0.83 | CDC25A (0.42) | HSP90AA1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7828948 | 0.82 | TBXAS1 (0.43) | HSP90AA1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL9664249 | 0.82 | MEN1 (0.44) | HSP90AA1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7829454 | 0.80 | HDAC1 (0.48) | MMP2 | |
| SCHEMBL7829923 | 0.79 | HDAC1 (0.49) | — | |
| SCHEMBL7832521 | 0.77 | CNR2 (0.39) | HSP90AA1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7821185 | 0.76 | CNR2 (0.40) | HSP90AA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7820846 | 0.76 | TNF (0.39) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL7831395 | 0.76 | CNR2 (0.38) | HSP90AA1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7833554 | 0.76 | CNR2 (0.38) | KMT2AALDH1A1CNR1CNR2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |