Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642517 | 1.00 | POLB (0.36) | POLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10972194 | 0.85 | L3MBTL1 (0.40) | POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9665368 | 0.83 | POLB (0.38) | POLBSMN1; SMN2HTT | |
| SCHEMBL10974747 | 0.83 | POLB (0.39) | POLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10972303 | 0.83 | L3MBTL1 (0.38) | POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9666268 | 0.83 | POLB (0.39) | POLBSMN1; SMN2HTT | |
| SCHEMBL9665754 | 0.82 | POLB (0.38) | POLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10973698 | 0.82 | RXFP1 (0.40) | L3MBTL1 | |
| SCHEMBL10579930 | 0.82 | POLB (0.38) | POLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9666465 | 0.81 | L3MBTL1 (0.38) | POLBSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |