Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000630 | 1.00 | RAB9A (0.60) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL9978289 | 0.88 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11049170 | 0.88 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL14935499 | 0.88 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11299049 | 0.86 | MAPT (0.67) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11296000 | 0.86 | MAPT (0.67) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL1578978 | 0.81 | MAPT (0.66) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11307663 | 0.81 | CYP19A1 (0.65) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11307656 | 0.81 | CYP19A1 (0.65) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL29809086 | 0.81 | CYP19A1 (0.65) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516409-A2 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-02 | — | — | EP | disclosed |