Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467735 | 0.86 | SMN1; SMN2 (0.54) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1750832 | 0.86 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4672474 | 0.82 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9665494 | 0.75 | SMN1; SMN2 (0.41) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11787743 | 0.73 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1750960 | 0.72 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL10332469 | 0.72 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4675793 | 0.72 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14434193 | 0.72 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9663956 | 0.71 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210647-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND INSECTICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| CN-1014240-B | Pyridazinone derivatives and process for preparing same | NISSAN CHEMICAL IND LTD (JP) | 1991-10-09 | — | — | CN | disclosed |
| US-4910201-A | With an ether substituted in position 5 | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| CN-86105510-A | The preparation method of pyridazinone derivative and insect-killing composition thereof | NISSAN CHEMICAL IND LTD | 1987-02-11 | — | — | CN | disclosed |
| EP-0210647-A2 | Pyridazinone derivatives, process for preparation thereof and insecticidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |