Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495725 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL5495723 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL9665548 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL9665555 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL5497313 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL5497310 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL5498119 | 0.84 | CYP1A2 (0.54) | ALDH1A1HSD17B10CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5498122 | 0.84 | CYP1A2 (0.54) | ALDH1A1HSD17B10CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5494847 | 0.79 | ATM (0.49) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL5494845 | 0.79 | ATM (0.49) | ALDH1A1HSD17B10TDP1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235345-B1 | INDENE COMPOUNDS | Taiyo Pharmaceutical Industry Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4876345-A | VASODILATORS, CALCIUM ANTAGONISTS; ANGINA PECTORIS | TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4762927-A | ANGINA PECTORIS | TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0235345-A1 | Indene compounds | Taiyo Pharmaceutical Industry Co., Ltd. (JP) | 1987-09-09 | — | — | EP | disclosed |