Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666955 | 0.79 | GAA (0.35) | GAAOPRK1CRBN | |
| SCHEMBL12408252 | 0.79 | RIPK1 (0.42) | GAA | |
| SCHEMBL4284897 | 0.77 | HDAC6 (0.54) | GAAOPRK1CRBN | |
| SCHEMBL9478999 | 0.74 | — | — | |
| SCHEMBL9666883 | 0.74 | — | — | |
| SCHEMBL25456037 | 0.74 | HRH3 (0.43) | GHSR | |
| SCHEMBL10515887 | 0.74 | HRH3 (0.43) | GHSR | |
| SCHEMBL14952797 | 0.72 | SMN1; SMN2 (0.60) | — | |
| SCHEMBL9479972 | 0.72 | SMN1; SMN2 (0.60) | — | |
| SCHEMBL2039884 | 0.72 | SMN1; SMN2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132392-B1 | ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1992-01-02 | — | — | EP | disclosed |
| EP-0304954-A2 | Cyclic dipeptide enantiomers | ICI AUSTRALIA LIMITED (AU) | 1989-03-01 | — | — | EP | disclosed |
| EP-0132392-A2 | Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1985-01-30 | — | — | EP | disclosed |