Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL9664928 | 0.94 | CYP2C19 (0.54) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| Benzylphenylether SCHEMBL6286650 | 0.85 | CYP2C19 (0.64) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| Benzylphenylether SCHEMBL27502543 | 0.85 | CYP2C19 (0.64) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| Benzylphenylether SCHEMBL18045520 | 0.85 | CYP2C19 (0.64) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| Phenoxymethylphosphonate SCHEMBL274327 | 0.85 | CYP2C9 (0.76) | CYP2C19LMNAPTPN1CYP2C9RAB9A | |
| SCHEMBL6794951 | 0.84 | LMNA (0.59) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL5861974 | 0.82 | LMNA (0.61) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6800341 | 0.82 | PTGS1 (0.61) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9664919 | 0.81 | PPARG (0.57) | CYP2C19LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL19668693 | 0.80 | PPARG (0.57) | CYP2C19LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |