Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665755 | 0.92 | CASR (0.38) | CASRF10USP30DPP4FAP | |
| SCHEMBL8954708 | 0.89 | CASR (0.39) | CASRF10USP30DPP4FAP | |
| SCHEMBL8954682 | 0.86 | ALOX5AP (0.38) | CASRF10USP30DPP4FAP | |
| SCHEMBL9665265 | 0.83 | CASR (0.40) | CASRF10USP30DPP4FAP | |
| SCHEMBL9710120 | 0.82 | F10 (0.38) | F10F2PRSS1 | |
| SCHEMBL9710184 | 0.81 | F10 (0.38) | F10HCRTR1HCRTR2F2PRSS1 | |
| SCHEMBL8954944 | 0.81 | CASR (0.38) | CASRF10PLAUKAT6A | |
| SCHEMBL9664145 | 0.80 | F10 (0.50) | F10PLAUF2 | |
| SCHEMBL8954993 | 0.79 | CASR (0.41) | CASRF10DPP4FAPDPP8 | |
| SCHEMBL9666086 | 0.79 | F10 (0.42) | F10PLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |