Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954772 | 0.89 | F10 (0.40) | CASRF10F2USP30PLAU | |
| SCHEMBL8954607 | 0.86 | CASR (0.36) | CASRF10PIN1KAT6AADAM17 | |
| SCHEMBL8954944 | 0.84 | CASR (0.38) | CASRF10PIN1PLAUKAT6A | |
| SCHEMBL9665029 | 0.83 | CASR (0.41) | CASRF10F2USP30PLAU | |
| SCHEMBL9710115 | 0.80 | F10 (0.37) | F10F2PLAU | |
| SCHEMBL9665283 | 0.80 | F10 (0.48) | F10F2PLAU | |
| Hydrochloric Acid SCHEMBL9664047 | 0.79 | F10 (0.48) | F10F2PLAU | |
| SCHEMBL8954708 | 0.79 | CASR (0.39) | CASRF10F2USP30PLAU | |
| SCHEMBL8954993 | 0.78 | CASR (0.41) | CASRF10F2PIN1KAT6A | |
| SCHEMBL9665755 | 0.77 | CASR (0.38) | CASRF10F2USP30PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |