Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472224 | 1.00 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7619905 | 1.00 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9578909 | 1.00 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11794783 | 1.00 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL434414 | 0.98 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2443584 | 0.93 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25222408 | 0.86 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL435538 | 0.85 | CYP3A4 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18115142 | 0.84 | TDP1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Biphenyl SCHEMBL8022864 | 0.83 | HDAC1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661876-A1 | METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF | University of Miami (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2025077836-A1 | IONIZABLE LIPIDS AND LIPID NANOPARTICLES FOR RNA DELIVERY | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-17 | — | — | WO | disclosed |
| CN-118772304-A | Quaternary phosphonium pullulan and preparation method and application thereof | 烟台先进材料与绿色制造山东省实验室 | 2024-10-15 | — | — | CN | disclosed |
| WO-2024168133-A1 | METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF MIAMI (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-116615251-A | Antibody-drug conjugates comprising GLP1 peptide mimetics and the uses thereof | 瑞泽恩制药公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115337297-A | CPI-613 mitochondrion targeted small molecule prodrug, self-assembled nanoparticles thereof, preparation method and application | 沈阳药科大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-105520941-B | Substituted gamma lactams as therapeutic agents | 阿勒根公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-110799516-A | Azithromycin derivatives containing phosphonium ions as anticancer agents | 来兴泰德基金会 | 2020-02-14 | — | — | CN | disclosed |
| EP-0273647-B1 | COUMARAN DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4921866-A | 1,3-dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4857516-A | Coumaran derivatives and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4837363-A | GASTRIC ACID SECRETION INHIBITORS, ANTIULCER AGENTS | GLAXO GROUP LIMITED (GB) | 1989-06-06 | — | — | US | disclosed |
| US-4824993-A | SYNTHETIC PROSTAGLANDINS, ANTISECRETORY AGENTS | GLAXO GROUP LIMITED (GB) | 1989-04-25 | — | — | US | disclosed |
| EP-0160495-B1 | CYCLOPENTYL ETHERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LTD (GB) | 1989-01-11 | — | — | EP | disclosed |
| EP-0273647-A1 | Coumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| EP-0160495-A2 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1985-11-06 | — | — | EP | disclosed |
| US-4536515-A | Substituted phenylalkenoic acids and esters | MERCK FROSST CANADA, INC. (CA) | 1985-08-20 | — | — | US | disclosed |
| US-4453005-A | Process for preparing substituted phenylalkenoic acids | MERCK FROSST CANADA, INC. (CA) | 1984-06-05 | — | — | US | disclosed |
| US-4420626-A | Dioxatricyclic prostacyclin analogs | E. R. SQUIBB & SONS, INC. (US) | 1983-12-13 | — | — | US | disclosed |
| US-4360685-A | Dioxatricyclic prostacyclin analogs | E. R. SQUIBB & SONS, INC. (US) | 1982-11-23 | — | — | US | disclosed |