Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794783 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7619905 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9665256 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9578909 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10472224 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2443584 | 0.94 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL435538 | 0.86 | CYP3A4 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25222408 | 0.84 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5453551 | 0.84 | TDP1 (0.63) | MAPTTDP1CYP3A4L3MBTL1LMNA | |
| Succinic Acid SCHEMBL7629002 | 0.82 | CYP3A4 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340571-B | Preparation method and application of novel artemisinin derivative and liposome | 中国中医科学院中药研究所 | 2024-09-27 | — | — | CN | claimed |
| US-20130184476-A1 | PREPARATION OF LUBIPROSTONE | DR. REDDY'S LABORATORIES LTD. (IN) | 2013-07-18 | — | — | US | claimed |
| JP-58124791-A | — | — | None | — | — | JP | disclosed |
| CN-115340571-B | Preparation method and application of novel artemisinin derivative and liposome | 中国中医科学院中药研究所 | 2024-09-27 | — | — | CN | disclosed |
| CN-118679165-A | Photodynamic therapy and diagnosis | RMW曹氏集团有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118010865-A | HPLC detection method for homologs in 4-carboxybutyltriphenylphosphine bromide | 时森海(杭州)医药科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019801-A | Fluoropolymer compositions and methods of making the same | 阿科玛股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117843599-A | Preparation method of prostaglandin intermediate containing 1-alkyl-1-alkenyl ethanol structure | 广州楷石医药有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115337297-B | CPI-613 mitochondrial targeting small molecule prodrug, self-assembled nanoparticle thereof, preparation method and application | 沈阳药科大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115160202-B | Preparation method of carboprost tromethamine and intermediate thereof | 广州楷石医药有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116615251-A | Antibody-drug conjugates comprising GLP1 peptide mimetics and the uses thereof | 瑞泽恩制药公司 | 2023-08-18 | — | — | CN | disclosed |
| US-4035392-A | Prostanoic acid intermediate | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4035414-A | Prostanoic acid derivatives | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4021477-A | 14-Chloro prostadienoic acid compounds | CARLO-ERBA S.P.A. (IT) | 1977-05-03 | — | — | US | disclosed |
| US-3987087-A | ANTI-ULCER, NASAL PATENCY, WOUND HEALING, LABOR INDUCEMENT | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3987085-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3975404-A | Bicyclic lactone intermediates | THE UPJOHN COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3969396-A | 8β, 11β, 12α-PGE2 compounds | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3954833-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3935254-A | 5C-PROSTEN-13-YNOIC ACIDS | CARLO ERBA S.P.A. (IT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184476-A1 | PREPARATION OF LUBIPROSTONE | PTGIR, PTGIS, VASP | HDAC3 3014/4885HDAC4 2586/4885HDAC1 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.