Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714489 | 0.80 | LAP3 (0.51) | LAP3ANPEPPOLBACP3TSHR | |
| SCHEMBL12876206 | 0.77 | LAP3 (0.49) | LAP3ANPEPPOLBACP3TSHR | |
| SCHEMBL9667088 | 0.76 | LAP3 (0.48) | LAP3ANPEPPOLBACP3TSHR | |
| SCHEMBL1241061 | 0.75 | POLB (0.49) | LAP3ANPEPPOLBNPSR1GAA | |
| SCHEMBL678819 | 0.74 | LAP3 (0.49) | LAP3ANPEPACP3 | |
| SCHEMBL3696122 | 0.74 | LAP3 (0.49) | LAP3ANPEPACP3 | |
| SCHEMBL677380 | 0.74 | LAP3 (0.49) | LAP3ANPEPACP3 | |
| SCHEMBL6772548 | 0.71 | ACP3 (0.51) | LAP3ANPEPPOLBACP3TSHR | |
| SCHEMBL9053712 | 0.71 | POLB (0.60) | LAP3ANPEPPOLBTSHRNPSR1 | |
| Amphetamine SCHEMBL4387791 | 0.71 | SLC6A4 (0.59) | LAP3ANPEPPOLBTSHRPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | claimed |
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |