Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.44 |
| ▸ | CYP21A2 | P08686 | 7/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.40 |
| ▸ | CYP7A1 | P22680 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665455 | 1.00 | USP2 (0.46) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL10675480 | 1.00 | USP2 (0.46) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL6151336 | 0.86 | CYP11B1 (0.53) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL10917859 | 0.86 | CYP11B1 (0.53) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL10921681 | 0.86 | CYP11B1 (0.53) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL10516594 | 0.76 | USP2 (0.45) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL9667152 | 0.76 | USP2 (0.45) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL9281611 | 0.76 | CYP3A4 (0.64) | USP2ALDH1A1LMNATSHRCYP17A1 | |
| SCHEMBL9281609 | 0.76 | CYP3A4 (0.64) | USP2ALDH1A1LMNATSHRCYP17A1 | |
| SCHEMBL7029531 | 0.74 | CYP21A2 (0.51) | USP2ALDH1A1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278105-B1 | 2,4,4-TRI- AND 2,2,4,4-TETRA-SUBSTITUTED-1,3-DIOXOLANE | SCHERING CORP (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0329711-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
| WO-1988005048-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1988-07-14 | — | — | WO | disclosed |