Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.53 |
| ▸ | CYP21A2 | P08686 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP7A1 | P22680 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10917859 | 1.00 | CYP11B1 (0.53) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL10921681 | 1.00 | CYP11B1 (0.53) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL9665448 | 0.86 | USP2 (0.46) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL9665455 | 0.86 | USP2 (0.46) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL10675480 | 0.86 | USP2 (0.46) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL394138 | 0.85 | CYP21A2 (0.61) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL29402298 | 0.85 | CYP21A2 (0.61) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9996071 | 0.84 | CYP21A2 (0.60) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL10516594 | 0.84 | USP2 (0.45) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 | |
| SCHEMBL9667152 | 0.84 | USP2 (0.45) | CYP11B1CYP17A1CYP21A2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409461-B1 | NOVEL AZOLE OR TRIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS FUNGICIDES | AVENTIS PHARMA SA (FR) | 2011-02-23 | — | — | EP | disclosed |
| US-6960600-B2 | Azole or triazole derivatives, method for preparing the same and use thereof as antifungal medicaments | AVENTIS PHARMA S.A. (FR) | 2005-11-01 | — | — | US | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1387837-B1 | NOVEL AZOLE OR TRIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS ANTIFUNGAL MEDICINES | AVENTIS PHARMA SA (FR) | 2005-07-27 | — | — | EP | disclosed |
| US-20040192922-A1 | Novel azole or triazole derivatives, method for preparing the same and use thereof as antifungal medicaments | AVENTIS PHARMA S.A. (FR) | 2004-09-30 | — | — | US | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1387837-A1 | NOVEL AZOLE OR TRIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS ANTIFUNGAL MEDICINES | Aventis Pharma S.A. (FR) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002090350-A1 | NOVEL AZOLE OR TRIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS ANTIFUNGAL MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-0278105-B1 | 2,4,4-TRI- AND 2,2,4,4-TETRA-SUBSTITUTED-1,3-DIOXOLANE | SCHERING CORP (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0077037-B1 | IMIDAZOLYLCARBOXYLIC ACIDS, THEIR DERIVATIVES AND PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-02-05 | — | — | EP | disclosed |
| EP-0054974-B1 | IMIDAZOLYLPROPANOL COMPOUNDS AND THEIR ACID ADDITION SALTS, AND PRODUCTION AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-07-10 | — | — | EP | disclosed |
| EP-0072623-B1 | IMIDAZOLE ANTIFUNGAL AGENTS | Pfizer Limited (GB) | 1985-06-05 | — | — | EP | disclosed |
| US-4461774-A | Antifungal imidazolylcarboxylic acids and their derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-24 | — | — | US | disclosed |
| US-4435399-A | 2-Aryl-1-(imidazol-1-yl)-8-(4-piperazin-1-ylphenoxy) octan-2-ol antifungal agents | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0098942-A1 | Optically active imidazolylpropanol compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-01-25 | — | — | EP | disclosed |
| EP-0077037-A1 | Imidazolylcarboxylic acids, their derivatives and production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-04-20 | — | — | EP | disclosed |
| EP-0072623-A1 | Imidazole antifungal agents | Pfizer Limited (GB) | 1983-02-23 | — | — | EP | disclosed |
| EP-0054974-A1 | Imidazolylpropanol compounds and their acid addition salts, and production and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-30 | — | — | EP | disclosed |
| EP-0023103-A1 | Antifungal imidazole derivatives, process for their preparation and pharmaceutical compositions thereof | Pfizer Limited (GB) | 1981-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192922-A1 | Novel azole or triazole derivatives, method for preparing the same and use thereof as antifungal medicaments | ERG28, CYP51A1, CYP3A7 | CYP11B1 8/4885CYP17A1 21/4885CYP21A2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.