Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040091 | 0.89 | TDP1 (0.38) | TDP1ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL10669928 | 0.83 | CA1 (0.52) | CA12CA1CA2CA14TSHR | |
| SCHEMBL1106979 | 0.81 | — | — | |
| SCHEMBL18462719 | 0.80 | CA14 (0.50) | ALDH1A1SMN1; SMN2CA12CA14TSHR | |
| SCHEMBL22266570 | 0.80 | CA14 (0.50) | ALDH1A1SMN1; SMN2CA12CA14TSHR | |
| SCHEMBL11434382 | 0.80 | CA14 (0.50) | ALDH1A1SMN1; SMN2CA12CA14TSHR | |
| SCHEMBL15478609 | 0.79 | — | — | |
| SCHEMBL3641120 | 0.79 | — | — | |
| SCHEMBL23637708 | 0.77 | — | — | |
| SCHEMBL18117417 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130041089-A1 | Fluorinated polyurethane composition | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-02-14 | — | — | US | disclosed |
| WO-2013017470-A1 | COMPOSITIONS OF IONISABLE FLUOROPOLYMERS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012175534-A1 | (PER)FLUOROPOLYETHER BLOCK COPOLYMERS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2012-12-27 | — | — | WO | disclosed |
| US-8318869-B2 | Fluorinated polyurethane composition | SOLVAY SOLEXIS S.P.A. (IT) | 2012-11-27 | — | — | US | disclosed |
| EP-2029185-B1 | MANUFACTURE OF MEDICAL IMPLANTS | SOLVAY SPECIALTY POLYMERS IT (IT) | 2012-02-22 | — | — | EP | disclosed |
| WO-2011131547-A1 | FLUORINATED POLYURETHANE COMPOSITION | SOLVAY SOLEXIS S.P.A. (IT) | 2011-10-27 | — | — | WO | disclosed |
| US-20110189395-A1 | Process for imparting grease, oil and water repellence to substrates | SOLVAY SOLEXIS S.P.A. (IT) | 2011-08-04 | — | — | US | disclosed |
| US-20100311893-A1 | Fluorinated polyurethane composition | SOLVAY SOLEXIS S.P.A. (IT) | 2010-12-09 | — | — | US | disclosed |
| US-20100227983-A1 | Manufacture of medical implants | SOLVAY SOLEXIS S.P.A. (IT) | 2010-09-09 | — | — | US | disclosed |
| WO-2008138927-A1 | FLUORINATED POLYURETHANE COMPOSITION | SOLVAY SOLEXIS S.P.A. (IT) | 2008-11-20 | — | — | WO | disclosed |
| WO-2007141317-A1 | MANUFACTURE OF MEDICAL IMPLANTS | SOLVAY SOLEXIS S.P.A. (IT) | 2007-12-13 | — | — | WO | disclosed |
| EP-1864685-A1 | Manufacture of medical implants | Solvay Solexis S.p.A. (IT) | 2007-12-12 | — | — | EP | disclosed |
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |