Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209937 | 0.81 | IDO1 (0.64) | IDO1GPR84SLC6A4HTTMEN1 | |
| SCHEMBL242245 | 0.80 | IDO1 (0.62) | IDO1SMN1; SMN2GPR84SLC6A4HTT | |
| SCHEMBL15330041 | 0.77 | IDO1 (0.72) | IDO1GPR84SLC6A4HTTGID4 | |
| SCHEMBL180403 | 0.77 | IDO1 (0.72) | IDO1GPR84SLC6A4HTTGID4 | |
| SCHEMBL17319346 | 0.75 | IDO1 (0.64) | IDO1GPR84SLC6A4HTTFFAR1 | |
| SCHEMBL17115833 | 0.74 | IDO1 (0.68) | IDO1GPR84SLC6A4HTTFFAR1 | |
| SCHEMBL2472307 | 0.74 | IDO1 (0.68) | IDO1GPR84SLC6A4HTTFFAR1 | |
| SCHEMBL7710711 | 0.74 | IDO1 (0.68) | IDO1GPR84SLC6A4HTTFFAR1 | |
| SCHEMBL12727345 | 0.74 | IDO1 (0.68) | IDO1GPR84SLC6A4HTTFFAR1 | |
| SCHEMBL298463 | 0.74 | IDO1 (0.68) | IDO1GPR84SLC6A4HTTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |