Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 12/20 | 0.74 |
| ▸ | F10 | P00742 | 6/20 | 0.73 |
| ▸ | PLAU | P00749 | 4/20 | 0.73 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.72 |
| ▸ | HPN | P05981 | 3/20 | 0.72 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.72 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | F12 | P00748 | 2/20 | 0.70 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.70 |
| ▸ | PROC | P04070 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954699 | 1.00 | PLG (0.74) | PLGF10PLAUST14HPN | |
| SCHEMBL8954940 | 0.91 | PLG (0.65) | PLGF10PLAUST14HPN | |
| SCHEMBL9710389 | 0.89 | F2 (0.70) | PLGF10PLAUST14HPN | |
| SCHEMBL8954840 | 0.89 | PLG (0.65) | PLGF10PLAUST14HPN | |
| SCHEMBL9664068 | 0.87 | F10 (0.71) | PLGF10PLAUST14HPN | |
| SCHEMBL8954939 | 0.86 | PLG (0.63) | PLGF10PLAUST14HPN | |
| SCHEMBL8954805 | 0.86 | PLG (0.66) | PLGF10PLAUHPNF12 | |
| SCHEMBL3310154 | 0.85 | MMP2 (0.71) | F2 | |
| SCHEMBL31086814 | 0.85 | MMP2 (0.71) | F2 | |
| SCHEMBL5189194 | 0.85 | MMP2 (0.71) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |