Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665195 | 0.98 | CCR1 (0.48) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL13123944 | 0.83 | CCR1 (0.48) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL5751962 | 0.80 | CCR1 (0.46) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL5754340 | 0.77 | KEAP1 (0.47) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL10391435 | 0.77 | CHRM2 (0.59) | KEAP1NFE2L2MEN1CYP2D6CHRM2 | |
| SCHEMBL7359773 | 0.75 | CCR1 (0.47) | CCR1MEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL8073914 | 0.74 | CCR1 (0.45) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL7362602 | 0.74 | MEN1 (0.40) | CCR1KEAP1NFE2L2MEN1CYP2D6 | |
| SCHEMBL8073924 | 0.74 | CCR1 (0.46) | CCR1MEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL9667120 | 0.74 | MEN1 (0.42) | MEN1HRH1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258617-B1 | 3,3-DISUBSTITUTED-PIPERIDINE-2,6-DIONE DERIVATIVES | MADAUS Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0258617-A1 | 3,3-Disubstituted-piperidine-2,6-dione derivatives | MADAUS Aktiengesellschaft (DE) | 1988-03-09 | — | — | EP | disclosed |