Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9667430 | 0.99 | GAA (0.39) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL10520019 | 0.91 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL10518805 | 0.89 | DRD1 (0.39) | DRD1DRD4DRD5DRD3DRD2 | |
| SCHEMBL9667382 | 0.87 | MEN1 (0.40) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9666361 | 0.87 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667637 | 0.87 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL10521009 | 0.86 | KDM4E (0.39) | DRD1DRD4DRD5ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9666414 | 0.86 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667280 | 0.86 | GAA (0.39) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667334 | 0.86 | MEN1 (0.36) | GAASMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259793-B1 | NAPHTHYL DERIVATIVES, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-4871735-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | DR. KARL THOMAE GMBH | 1989-10-03 | — | — | US | disclosed |
| EP-0259793-A1 | Naphthyl derivatives, medicaments containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |