Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9668438 | 0.99 | GPR84 (0.36) | MEN1KMT2AGPR84PDE4AATM | |
| SCHEMBL9667382 | 0.95 | MEN1 (0.40) | MEN1KMT2AGPR84PDE4AATM | |
| SCHEMBL9667498 | 0.86 | GAA (0.40) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL9668308 | 0.86 | MEN1 (0.40) | MEN1KMT2AGPR84PDE4AATM | |
| Hydrochloric Acid SCHEMBL9667430 | 0.85 | GAA (0.39) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL9667669 | 0.83 | HSD11B1 (0.36) | — | |
| SCHEMBL10521009 | 0.83 | KDM4E (0.39) | KMT2AKDM4EALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL10519607 | 0.82 | KDM4E (0.39) | KMT2AKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL10518805 | 0.82 | DRD1 (0.39) | KDM4EALDH1A1TSHRHSD17B10KRAS | |
| SCHEMBL10694975 | 0.82 | MTNR1B (0.39) | PDE4AALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259793-B1 | NAPHTHYL DERIVATIVES, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0347066-A1 | New enantiomers and their isolation | H. LUNDBECK A/S (DK) | 1989-12-20 | — | — | EP | disclosed |
| US-4871735-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | DR. KARL THOMAE GMBH | 1989-10-03 | — | — | US | disclosed |
| EP-0259793-A1 | Naphthyl derivatives, medicaments containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |