Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609023 | 0.82 | DDB1 (0.54) | SMN1; SMN2TDP1RAB9AL3MBTL1 | |
| SCHEMBL9666140 | 0.78 | POLB (0.43) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL10553476 | 0.78 | RAB9A (0.42) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL10552079 | 0.78 | CYP2C9 (0.39) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL10556941 | 0.77 | TDP1 (0.42) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL10553402 | 0.77 | TDP1 (0.42) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL9667938 | 0.76 | TDP1 (0.43) | TDP1RAB9A | |
| SCHEMBL9667725 | 0.76 | TDP1 (0.41) | POLBSMN1; SMN2HTR2ATDP1RAB9A | |
| SCHEMBL9666874 | 0.76 | TDP1 (0.47) | SMN1; SMN2TDP1RAB9A | |
| SCHEMBL10726590 | 0.76 | HTR2A (0.48) | HTR2ATDP1RAB9AIDO1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |