Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666235 | 0.90 | LMNA (0.58) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9668000 | 0.88 | LMNA (0.56) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10406905 | 0.84 | LMNA (0.64) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL148765 | 0.84 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL29695838 | 0.84 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16518632 | 0.83 | LMNA (0.81) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL203110 | 0.83 | LMNA (0.98) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11009907 | 0.82 | MEN1 (0.81) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL27973383 | 0.82 | LMNA (0.96) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9668529 | 0.82 | KDM4E (0.52) | LMNAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324298-B1 | 7-(1-AZETIDINYL)-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-12-23 | — | — | EP | claimed |
| US-4927926-A | BACTERICIDES | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1990-05-22 | — | — | US | disclosed |