SCHEMBL966812

SCHEMBL966812

CC(C)OC(=O)C(CS)[Zn]C(CS)C(=O)OC(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963005 0.77 TSHR (0.39) TSHR
SCHEMBL1363269 0.75 TSHR (0.42) TSHRLMNAHCAR2
SCHEMBL967678 0.72 HCAR2 (0.35) TSHRLMNAHCAR2
SCHEMBL4122570 0.71 PTGS1 (0.46) TSHRLMNAHCAR2
SCHEMBL4122573 0.71 PTGS1 (0.46) TSHRLMNAHCAR2
SCHEMBL963290 0.70 TSHR (0.42) TSHRLMNAHCAR2
Hydrochloric Acid SCHEMBL8596085 0.70 PTGS1 (0.44) TSHRLMNAHCAR2
SCHEMBL6735619 0.70 TSHR (0.37) TSHRLMNAHCAR2
Hydrochloric Acid SCHEMBL9589944 0.70 PTGS1 (0.44) TSHRLMNAHCAR2
SCHEMBL28897693 0.67 TSHR (0.43) TSHRLMNAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed