SCHEMBL4122573

SCHEMBL4122573

CC(C)OC(=O)[C@@H](N)CS

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
TSHR P16473 1/20 0.39
ENPEP Q07075 6/20 0.38
SLC7A5 Q01650 1/20 0.33
LMNA P02545 2/20 0.32
ANPEP P15144 3/20 0.31
HCAR2 Q8TDS4 1/20 0.31
ERAP2 Q6P179 1/20 0.31
ERAP1 Q9NZ08 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4122570 1.00 PTGS1 (0.46) PTGS1SLC7A11TSHRENPEPSLC7A5
Hydrochloric Acid SCHEMBL9589944 0.98 PTGS1 (0.44) PTGS1SLC7A11TSHRENPEPSLC7A5
Hydrochloric Acid SCHEMBL8596085 0.98 PTGS1 (0.44) PTGS1SLC7A11TSHRENPEPSLC7A5
SCHEMBL24359844 0.81 PTGS1 (0.41) PTGS1SLC7A11ENPEPSLC7A5
SCHEMBL23408842 0.81 SLC7A5 (0.43) PTGS1SLC7A11ENPEPSLC7A5ANPEP
SCHEMBL6535208 0.80 PTGS1 (0.44) PTGS1SLC7A11ENPEPSLC7A5ANPEP
SCHEMBL5330308 0.79 TSHR (0.40) TSHRSLC7A5LMNAHCAR2CA12
SCHEMBL9384783 0.79 PTGS1 (0.48) PTGS1SLC7A11ENPEPANPEP
SCHEMBL30606392 0.79 TSHR (0.40) TSHRSLC7A5LMNAHCAR2CA12
SCHEMBL13155620 0.79 TSHR (0.40) TSHRSLC7A5LMNAHCAR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
EP-4619503-A1 OPTIMIZED ACHROMOSOMAL DYNAMIC ACTIVE SYSTEMS AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2025-09-24 EP claimed
US-20250059236-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 BICYCLETX LIMITED (GB) 2025-02-20 US claimed
WO-2024107853-A1 OPTIMIZED ACHROMOSOMAL DYNAMIC ACTIVE SYSTEMS AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-05-23 WO claimed
CN-113204788-B Fine granularity attribute matching privacy protection method 广州大学 2023-06-16 CN claimed
CN-109477840-A For non-destructively determining the method and system of Fowl Sex in ovum 因欧沃私人有限责任公司 2019-03-15 CN claimed
EP-1603549-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS Yu, Ruey J., Dr. (US) 2005-12-14 EP claimed
US-20040220264-A1 Bioavailability and improved delivery of acidic pharmaceutical drugs YU RUEY J 2004-11-04 US claimed
WO-2004082628-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS YU RUEY J (US) 2004-09-30 WO claimed
US-20260150129-A1 Communication Method, Apparatus, and System HUAWEI TECHNOLOGIES CO., LTD. (CN) 2026-05-28 US disclosed
US-20260117695-A1 EPIC Cycles for the EPIC Cycle Engine UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2026-04-30 US disclosed
US-20260002925-A1 NANOPORE SYSTEMS AND METHODS FOR SINGLE-MOLECULE POLYMER PROFILING UNIV GRONINGEN (NL) 2026-01-01 US disclosed
EP-4619503-A1 OPTIMIZED ACHROMOSOMAL DYNAMIC ACTIVE SYSTEMS AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2025-09-24 EP disclosed
CN-120118841-A Composition, induction method and application of chemical reprogramming induction functional ciRPE cells 瓯江实验室 2025-06-10 CN disclosed
EP-1603549-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS Yu, Ruey J., Dr. (US) 2005-12-14 EP disclosed
US-20040220264-A1 Bioavailability and improved delivery of acidic pharmaceutical drugs YU RUEY J 2004-11-04 US disclosed
WO-2004082628-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS YU RUEY J (US) 2004-09-30 WO disclosed
WO-1998055135-A1 PROTECTIVE COMPOSITIONS THE SECRETARY OF STATE FOR DEFENCE (GB) 1998-12-10 WO disclosed
EP-0546063-A1 TOXIC AGENT PROTECTIVE COMPOUNDS, COMPOSITIONS AND USES The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1993-06-16 EP disclosed
WO-1992004024-A2 TOXIC AGENT PROTECTIVE COMPOUNDS, COMPOSITIONS AND METHOD THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630588-B2 Bicyclic peptide ligands specific for CD137 PTMS, IL36G, HLA-A PTGS1 4223/4885SLC7A11 1904/4885TSHR 403/4885
US-20260150129-A1 Communication Method, Apparatus, and System STUB1, CBLC, CHRNA2 PTGS1 4474/4885SLC7A11 1255/4885TSHR 2302/4885
US-20260002925-A1 NANOPORE SYSTEMS AND METHODS FOR SINGLE-MOLECULE POLYMER PROFILING SLC9A2, SLC10A6, NUP210 PTGS1 4013/4885SLC7A11 580/4885TSHR 1211/4885
US-20260117695-A1 EPIC Cycles for the EPIC Cycle Engine CCNI, AXIN2, CTNNB1 PTGS1 4688/4885SLC7A11 3665/4885TSHR 4184/4885
US-20250059236-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR CD137 CD2BP2, CD40, SDC1 PTGS1 4353/4885SLC7A11 2834/4885TSHR 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.