Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830527 | 0.86 | CTRC (0.45) | CTRCBCL2L1BADPTPN1NQO1 | |
| SCHEMBL8830529 | 0.86 | CTRC (0.45) | CTRCBCL2L1BADPTPN1NQO1 | |
| SCHEMBL6682317 | 0.76 | CTRC (0.50) | CTRCBCL2L1BADNQO1GRIA1 | |
| SCHEMBL836449 | 0.73 | CTRC (0.47) | CTRCBCL2L1BADNQO1GRIA1 | |
| SCHEMBL29442687 | 0.73 | CTRC (0.47) | CTRCBCL2L1BADNQO1GRIA1 | |
| SCHEMBL8830364 | 0.73 | EGFR (0.48) | CTRC | |
| SCHEMBL8830363 | 0.73 | EGFR (0.48) | CTRC | |
| SCHEMBL368712 | 0.71 | BCL2L1 (0.41) | CTRCBCL2L1BADNQO1GRIA1 | |
| SCHEMBL8830401 | 0.68 | EGFR (0.47) | CTRC | |
| SCHEMBL8830404 | 0.68 | EGFR (0.47) | CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470221-A1 | NEW ARYL- AND HETEROARYLETHENYLENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1992-02-12 | — | — | EP | disclosed |