Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959591 | 0.89 | XIAP (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10653187 | 0.88 | GRB2 (0.43) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10701287 | 0.87 | XIAP (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10653313 | 0.85 | GRB2 (0.43) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL29391363 | 0.81 | GRB2 (0.55) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL29978208 | 0.81 | MAPK8 (0.50) | GRB2NTSR2NTSR1SORT1NPY1R | |
| SCHEMBL29441906 | 0.81 | NPY1R (0.43) | XIAPGRB2NTSR2NTSR1SORT1 | |
| SCHEMBL29636207 | 0.80 | GRB2 (0.49) | DPP4DPP7XIAPGRB2OPRM1 | |
| SCHEMBL23256152 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1 | |
| SCHEMBL5056855 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096811-A | Tripeptide chloromethyl ketone enzyme inhibitor | GENENTECH, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0237332-A1 | Assay for thrombosis-related materials | GENENTECH, INC. (US) | 1987-09-16 | — | — | EP | disclosed |