Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823239 | 0.78 | KMT2A (0.43) | TAAR1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL1072945 | 0.75 | CYP3A4 (0.42) | KMT2AALDH1A1HPGDHTTMAOA | |
| SCHEMBL12038285 | 0.72 | MAOA (0.50) | TAAR1KMT2AMAOAMAOB | |
| SCHEMBL1824872 | 0.69 | MAOA (0.52) | TAAR1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL5128321 | 0.69 | POLB (0.42) | KMT2APOLBALDH1A1KDM4ENPC1 | |
| SCHEMBL10622669 | 0.69 | MAOA (0.39) | ALDH1A1KDM4ETDP1MAOAMAOB | |
| SCHEMBL1536180 | 0.68 | MAOA (0.35) | TAAR1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL12813543 | 0.68 | MAOA (0.50) | TAAR1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL111635 | 0.68 | TAAR1 (0.68) | TAAR1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL9491792 | 0.67 | TAAR1 (0.74) | TAAR1KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287907-B1 | Pyrazolo[3,4-d]pyrimidines, process for their preparation and use as pharmaceutical compounds | Roche Diagnostics GmbH (DE) | 1992-08-19 | — | — | EP | disclosed |