Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | KAT7 | O95251 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314168 | 0.93 | KDM4E (0.49) | ACKR3FEN1ALOX5APBRD4USP30 | |
| SCHEMBL31314345 | 0.93 | KDM4E (0.49) | ACKR3FEN1ALOX5APBRD4USP30 | |
| SCHEMBL31314279 | 0.89 | NAMPT (0.50) | FEN1ALOX5APSCN9ABRD4USP30 | |
| SCHEMBL24742264 | 0.89 | NAMPT (0.50) | FEN1ALOX5APSCN9ABRD4USP30 | |
| SCHEMBL6522277 | 0.86 | KDM4E (0.54) | KDM4EPKM | |
| SCHEMBL29244762 | 0.84 | ACKR3 (0.51) | ACKR3KDM1AFEN1BACE1CTSD | |
| SCHEMBL21605864 | 0.84 | ACKR3 (0.51) | ACKR3KDM1AFEN1BACE1CTSD | |
| SCHEMBL23871348 | 0.84 | ACKR3 (0.51) | ACKR3KDM1AFEN1BACE1CTSD | |
| SCHEMBL31055033 | 0.81 | MEN1 (0.50) | ACKR3KDM1ABACE1CTSDBRD4 | |
| SCHEMBL2069052 | 0.81 | FEN1 (0.48) | ACKR3KDM1AFEN1BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024263708-A2 | ORNITHINE DECARBOXYLASE (ODC) INHIBITORS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2024-12-26 | — | — | WO | disclosed |
| EP-0495750-A2 | Heterocyclic hydroxylamine | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |