SCHEMBL31055033

SCHEMBL31055033

CC(C)(C)OC(=O)N1CCCC(C(=O)ON2C(=O)c3ccccc3C2=O)C1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
BRD4 O60885 1/20 0.45
USP30 Q70CQ3 2/20 0.45
ACKR3 P25106 1/20 0.43
HPGD P15428 1/20 0.43
HSD11B1 P28845 1/20 0.43
GPR119 Q8TDV5 2/20 0.42
HPGDS O60760 1/20 0.42
KDM1A O60341 1/20 0.42
BACE1 P56817 2/20 0.41
CTSD P07339 1/20 0.41
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PKM P14618 1/20 0.41
FPR2 P25090 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23779835 0.93 GPR119 (0.46) KMT2ABRD4USP30HPGDGPR119
SCHEMBL25261256 0.88 NAMPT (0.46) BRD4USP30GPR119KDM4EPKM
SCHEMBL22715442 0.86 GPR119 (0.51) KMT2AHPGDGPR119KDM4EPKM
SCHEMBL4268317 0.82 PRMT5 (0.51) MEN1KMT2AALDH1A1MAPTBRD4
SCHEMBL9668952 0.81 ACKR3 (0.49) BRD4USP30ACKR3KDM1ABACE1
SCHEMBL30022565 0.81 NAMPT (0.40) BRD4USP30GPR119KDM4EPKM
SCHEMBL31510905 0.80 EPHX2 (0.51) MEN1KMT2AALDH1A1USP30HPGD
SCHEMBL28459867 0.80 EPHX2 (0.51) MEN1KMT2AALDH1A1USP30HPGD
SCHEMBL30537463 0.80 EPHX2 (0.51) MEN1KMT2AALDH1A1USP30HPGD
SCHEMBL1025817 0.79 TMEM97 (0.54) MEN1KMT2AALDH1A1MAPTBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665454-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-12-24 EP disclosed
WO-2024173173-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2024-08-22 WO disclosed