SCHEMBL9669192

SCHEMBL9669192

O=C1C(=O)N(C(=O)c2c3ccccc3nc3ccccc23)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 8/20 0.56
CTRB1 P17538 1/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
IDO1 P14902 2/20 0.47
TDO2 P48775 2/20 0.47
IDO2 Q6ZQW0 2/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
NTRK1 P04629 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
HTT P42858 1/20 0.47
MAPK8 P45983 1/20 0.47
RAB9A P51151 1/20 0.47
NTRK2 Q16620 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
ALDH1A1 P00352 4/20 0.41
BCHE P06276 3/20 0.41
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9714116 0.78 CES1 (0.54) CES1CTRB1KMT2AMAPTALDH1A1
SCHEMBL10353187 0.77 CES1 (0.64) CES1CTRB1KMT2AALDH1A1BCHE
SCHEMBL21271823 0.75 BCHE (0.57) CES1CTRB1KMT2AMAPTLMNA
SCHEMBL5739235 0.74 CES1 (0.70) CES1CTRB1ALDH1A1BCHEGAA
SCHEMBL4989864 0.73 CES1 (1.00) CES1CTRB1KMT2AMAPTHTT
SCHEMBL30070852 0.73 CES1 (1.00) CES1CTRB1KMT2AMAPTHTT
SCHEMBL27686651 0.72 CES1 (0.72) CES1CTRB1KMT2AALDH1A1BCHE
SCHEMBL9236314 0.72 CES1 (0.72) CES1CTRB1KMT2AALDH1A1BCHE
SCHEMBL9667222 0.72 CES1 (0.47) CES1CTRB1KMT2AMAPTALDH1A1
SCHEMBL9713992 0.72 CES1 (0.47) CES1CTRB1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511366-A1 CHEMILUMINESCENT COMPOUNDS BECKMAN INSTRUMENTS, INC. (US) 1992-11-04 EP disclosed
WO-1992009580-A1 CHEMILUMINESCENT COMPOUNDS BECKMAN INSTRUMENTS, INC. (US) 1992-06-11 WO disclosed