Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | PTAFR | P25105 | 19/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471373 | 0.97 | OPRK1 (0.75) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9667874 | 0.96 | OPRK1 (0.74) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10471499 | 0.96 | OPRK1 (0.74) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10469753 | 0.96 | OPRK1 (0.74) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10469718 | 0.91 | PTAFR (0.88) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10471094 | 0.90 | OPRK1 (0.76) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9525884 | 0.89 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10464347 | 0.89 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9525077 | 0.89 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9522397 | 0.89 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230942-B1 | THIENO-1,4-DIAZEPINES | BOEHRINGER INGELHEIM KG (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |