Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425523 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL29565442 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL14698753 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL10542563 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL9143592 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL20570432 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL10851006 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL30660870 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9GAAMAPT | |
| SCHEMBL14587496 | 0.78 | CA12 (0.44) | ALDH1A1CYP1A2CYP2C9GAAKMT2A | |
| SCHEMBL7850554 | 0.77 | GAA (0.47) | ALDH1A1CYP1A2CYP2C9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177940-B1 | HYDRAZINE DERIVATIVES AND THEIR USE | E.R. Squibb & Sons, Inc. (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| US-5037983-A | 6,7-dihydroxyquinoxalines as intermediates to beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4904775-A | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0342423-A2 | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1989-11-23 | — | — | EP | disclosed |