SCHEMBL9670259

SCHEMBL9670259

Cc1ccc2nc(SCc3ccccn3)n(-c3ccccc3)c(=O)c2c1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 3/20 0.76
PNP P00491 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9672681 0.88 PDE7A (0.85) PDE7A
SCHEMBL9671578 0.87 PDE7A (0.76) PDE7A
SCHEMBL9670401 0.87 PDE7A (0.76) PDE7A
SCHEMBL9671403 0.86 PDE7A (1.00) PDE7A
SCHEMBL9670686 0.83 PDE7A (0.73) PDE7A
Chloroform SCHEMBL10585238 0.83 PDE7A (0.70) PDE7A
SCHEMBL9670279 0.82 PNP (0.58) PNP
SCHEMBL9670297 0.82 PDE7A (0.78) PDE7A
SCHEMBL9381672 0.81 PDE7A (0.80) PDE7A
SCHEMBL9670342 0.80 PDE7A (0.72) PDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276825-B1 4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS NISSHIN FLOUR MILLING CO., LTD. (JP) 1992-09-09 EP disclosed
EP-0276826-B1 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS NISSHIN FLOUR MILLING CO., LTD. (JP) 1991-12-27 EP disclosed
US-5008266-A Antiulcer agent NISSHIN FLOUR MILLING CO., LTD. (JP) 1991-04-16 US disclosed
US-4861780-A 4(3H)-quinazolinone derivatives and pharmaceutical compositions NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-08-29 US disclosed
US-4833144-A ANTIULCER AGENTS NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-05-23 US disclosed
EP-0276826-A1 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions NISSHIN FLOUR MILLING CO., LTD. (JP) 1988-08-03 EP disclosed
EP-0276825-A1 4 (3H)-Quinazolinone derivatives, processes for their preparation and pharmaceutical compositions NISSHIN FLOUR MILLING CO., LTD. (JP) 1988-08-03 EP disclosed